Glycosylation Analysis Service for SARS-CoV Glycoprotein

SARS-CoV Glycoprotein

SARS-CoV is a type of coronavirus responsible for causing the outbreak of severe acute respiratory syndrome (SARS) identified in 2002-2003. It is classified as an enveloped virus with a single-stranded RNA genome. The virus is characterized by spike glycoprotein (S) structures on its surface, which play a crucial role in interacting with host receptors to facilitate cellular entry. The SARS-CoV S glycoprotein is a precursor polypeptide that consists of 1255 amino acids and harbors 23 potential N-linked glycosylation sites. Previous investigations have confirmed the occupancy of several sites, revealing the presence of both complex-type and high mannose-type N-glycans, which suggests that glycans present on the surface of the SARS-CoV S glycoprotein may be involved in the attachment of the virus to host cells expressing specific cell surface lectins. Consequently, the analysis of the glycan profile holds significant potential for providing insights into potential therapeutic strategies and contributing to the development of vaccines targeted at combating SARS-CoV and related viruses.

Glycosylation Analysis Services for SARS-CoV Glycoprotein at Creative Biolabs

Creative Biolabs offers viral glycosylation analysis services, including for SARS-CoV, to assist researchers in unraveling the intricate details of glycosylation. Our expertise encompasses a wide array of glycosylation analytical approaches that can be customized to suit the specific needs of each project. We provide end-to-end services, from sample preparation to the delivery of comprehensive reports, with our experts guiding you at every stage of the process.

Our specialization lies in high-throughput and in-depth glycoprofiling, facilitated by a comprehensive portfolio of UPLC-QTOF-MS/MS methods. Our services encompass a comprehensive range of analyses, including intact glycopeptide analysis, glycopeptide mapping and site occupancy determination, glycan profiling, and structure and abundance analysis.

One-Stop Services

Recombinant viral protein expression, purification, and characterization
In-gel digestion (protein characterization with SDS-PAGE)
Proteolytic digestion
Glycan labeling with various techniques
Glycan sequencing through exo-glycosidase digestion
Glycosylation analysis with UPLC-MS/MS methods
Data interpretation and report output

Highlights

Specialized workflow for glycan analysis
Latest equipment with high-resolution and mass accuracy
Robust methods to enhance glycopeptide analysis
Professional team experienced in glycan analysis
Best after-sale service

At Creative Biolabs, a comprehensive range of services in SARS-CoV glycoprotein analysis are designed to support researchers and scientists in gaining a comprehensive understanding of glycoproteins, facilitating advancements in various fields, including virology and vaccine development. Our team of experts is dedicated to assisting you throughout each step of your project to ensure precise and insightful results. Contact us today to learn more about how we can help support your programs.

For Research Use Only.

Glycosylation Analysis Service for SARS-CoV Glycoprotein

SARS-CoV Glycoprotein

Glycosylation Analysis Services for SARS-CoV Glycoprotein at Creative Biolabs

One-Stop Services

Highlights

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