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NativeExtract™ Human APLNR Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX364)

This product is recombinant Human APLNR protein in native nanodisc form. The synthetic compound we developed can solubilize the APLNR protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • APLNR
  • Protein Length
  • Full length
  • Molecular Weight
  • 42.7 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • APLNR
  • Full Name
  • Apelin receptor
  • Introduction
  • This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified.
  • Alternative Names
  • APJ; APJR; HG11; AGTRL1; APJ (apelin) receptor; APJ receptor; G protein-coupled receptor APJ; G-protein coupled receptor HG11; HG11 orphan receptor; angiotensin II receptor-like 1; angiotensin receptor-like 1; APLNR; Apelin receptor

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