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NativeExtract™ Human CLDN4 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX410)

Datasheet
This product is recombinant Human CLDN4 protein in native nanodisc form. The synthetic compound we developed can solubilize the CLDN4 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CLDN4
  • Protein Length
  • Full length
  • Molecular Weight
  • 22.1 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • CLDN4
  • Full Name
  • Claudin 4
  • Introduction
  • The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.
  • Alternative Names
  • CPER; CPE-R; CPETR; CPETR1; WBSCR8; hCPE-R; claudin-4; CPE-receptor; Clostridium perfringens enterotoxin receptor 1; Williams-Beuren syndrome chromosomal region 8 protein; CLDN4; Claudin 4

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