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NativeExtract™ Human DRD3 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX282)

Datasheet
This product is recombinant Human DRD3 protein in native nanodisc form. The synthetic compound we developed can solubilize the DRD3 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • DRD3
  • Protein Length
  • Full length
  • Molecular Weight
  • 44.2kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • DRD3
  • Full Name
  • Dopamine receptor D3
  • Introduction
  • This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).
  • Alternative Names
  • D3DR; ETM1; FET1; D(3) dopamine receptor; essential tremor 1; DRD3; Dopamine receptor D3

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