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NativeExtract™ Human GABBR1 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX262)

Datasheet
This product is recombinant Human GABBR1 protein in native nanodisc form. The synthetic compound we developed can solubilize the GABBR1 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GABBR1
  • Protein Length
  • Full length
  • Molecular Weight
  • 108.3kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • GABBR1
  • Full Name
  • Gamma-aminobutyric acid type B receptor subunit 1
  • Introduction
  • This gene encodes a receptor for gamma-aminobutyric acid (GABA), which is the main inhibitory neurotransmitter in the mammalian central nervous system. This receptor functions as a heterodimer with GABA(B) receptor 2. Defects in this gene may underlie brain disorders such as schizophrenia and epilepsy. Alternative splicing generates multiple transcript variants, but the full-length nature of some of these variants has not been determined.
  • Alternative Names
  • GB1; GPRC3A; GABABR1; GABBR1-3; GABA-B receptor, R1 subunit; gamma-aminobutyric acid (GABA) B receptor, 1; seven transmembrane helix receptor; GABBR1; Gamma-aminobutyric acid type B receptor subunit 1

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