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NativeExtract™ Human HTR6 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX342)

Datasheet
This product is recombinant Human HTR6 protein in native nanodisc form. The synthetic compound we developed can solubilize the HTR6 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • HTR6
  • Protein Length
  • Full length
  • Molecular Weight
  • 47kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • HTR6
  • Full Name
  • 5-hydroxytryptamine receptor 6
  • Introduction
  • This gene encodes a protein that belongs to the seven-transmembrane G protein-coupled receptor family of proteins. The encoded protein couples with the Gs alpha subunit and stimulates adenylate cyclase to activate the cyclic AMP-dependent signaling pathway. This receptor is thought to regulate cholinergic neuronal transmission in the brain. Several antidepressants and antipsychotic drugs have a high affinity for this receptor.
  • Alternative Names
  • 5-HT6; 5-HT6R; 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled; serotonin receptor 6; HTR6; 5-hydroxytryptamine receptor 6

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