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NativeExtract™ Human MC3R Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX168)

Datasheet
This product is recombinant Human MC3R protein in native nanodisc form. The synthetic compound we developed can solubilize the MC3R protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • MC3R
  • Protein Length
  • Full length
  • Molecular Weight
  • 36kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • MC3R
  • Full Name
  • Melanocortin 3 receptor
  • Introduction
  • This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans.
  • Alternative Names
  • MC3; OB20; OQTL; BMIQ9; MC3-R; melanocortin receptor 3; obesity quantitative trait locus; MC3R; Melanocortin 3 receptor

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