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NativeExtract™ Human PLA2R1 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX451)

Datasheet
This product is recombinant Human PLA2R1 protein in native nanodisc form. The synthetic compound we developed can solubilize the PLA2R1 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • PLA2R1
  • Protein Length
  • Full length
  • Molecular Weight
  • 168.6 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • PLA2R1
  • Full Name
  • Phospholipase A2 receptor 1
  • Introduction
  • This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.
  • Alternative Names
  • PLA2R1; PLA2R; PLA2-R; PLA2IR; CLEC13C; PLA2G1R; secretory phospholipase A2 receptor; 180 kDa secretory phospholipase A2 receptor; C-type lectin domain family 13 member C; M-type receptor; phospholipase A2 receptor 1, 180kD; phospholipase A2 receptor 1, 180kDa; Phospholipase A2 receptor 1

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