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NativeExtract™ Human PTGFR Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX67)

This product is recombinant Human PTGFR protein in native nanodisc form. The synthetic compound we developed can solubilize the PTGFR protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • PTGFR
  • Protein Length
  • Full length
  • Molecular Weight
  • 40.1kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • PTGFR
  • Full Name
  • Prostaglandin F receptor
  • Introduction
  • The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • FP; prostaglandin F2-alpha receptor; FP prostanoid receptor; PGF receptor; PGF2 alpha receptor; prostaglandin receptor (2-alpha); prostanoid FP receptor; PTGFR; Prostaglandin F receptor

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