Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
With over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications.
Creative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
With deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
Get a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
Recombinant full-length human ACKR4 protein reconstituted in a nanodisc membrane-mimetic system for biochemical, binding, and assay development applications.
The construct includes an N-terminal FLAG tag and a C-terminal Rho1D4 tag.
Protein Format
Nanodisc
Purity
The protein purity is greater than 90% as determined by SDS-PAGE.
Target
Target Protein
ACKR4
Full Name
atypical chemokine receptor 4
Introduction
Atypical chemokine receptor 4 (ACKR4) is a full-length human gpcr. Atypical Chemokine Receptor 4 (ACKR4) acts as a scavenger that internalizes and degrades homeostatic chemokines (CCL19, CCL21, CCL25, and CCL20), thereby generating the precise directional gradients necessary for proper immune cell trafficking into lymph nodes. Because it controls the spatial positioning of T cells and dendritic cells, modulating ACKR4 is a high-priority strategy to either rescue defective anti-tumor immunity in checkpoint-resistant cancers or mitigate unchecked leukocyte recruitment in inflammatory diseases. The protein is supplied in an MSP-free, copolymer-stabilized native-lipid nanodisc. The preparation uses 2-step purification.