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NativeExtract™ Recombinant Full Length Human ADRB1 Protein (Nanodisc, FLAG-tagged) (CAT#: SYF-0426-CW8)

This product is recombinant Human ADRB1 protein in native nanodisc form. The synthetic compound we developed can solubilize the ADRB1 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ADRB1
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 51.2 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • ADRB1
  • Full Name
  • Adrenoceptor Beta 1
  • Introduction
  • The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Beta-1 adrenoceptors are predominately located in the heart. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure.
  • Alternative Names
  • RHR; B1AR; FNSS2; ADRB1R; BETA1AR

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