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NativeExtract™ Recombinant Full Length Human ACHB Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW70)

This product is recombinant Human ACHB protein in native nanodisc form. The synthetic compound we developed can solubilize the ACHB protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ACHB
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 56.7 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • ACHB
  • Full Name
  • Cholinergic Receptor Nicotinic Beta 1 Subunit
  • Introduction
  • The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.
  • Alternative Names
  • Cholinergic Receptor Nicotinic Beta 1 Subunit; Cholinergic Receptor, Nicotinic, Beta Polypeptide 1 (Muscle); Acetylcholine Receptor, Nicotinic, Beta 1 (Muscle); Cholinergic Receptor, Nicotinic, Beta 1 (Muscle); Cholinergic Receptor, Nicotinic Beta 1; CHRNB; ACHRB

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