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NativeExtract™ Recombinant Full Length Human ICLN Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW63)

This product is recombinant Human BRS3 protein in native nanodisc form. The synthetic compound we developed can solubilize the BRS3 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ICLN
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 26.2 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • ICLN
  • Full Name
  • Chloride Nucleotide-Sensitive Channel 1A
  • Introduction
  • This gene encodes a protein that functions in multiple regulatory pathways. The encoded protein complexes with numerous cytosolic proteins and performs diverse functions including regulation of small nuclear ribonucleoprotein biosynthesis, platelet activation and cytoskeletal organization. The protein is also found associated with the plasma membrane where it functions as a chloride current regulator. Pseudogenes of this gene are found on chromosomes 1, 4 and 6. Several transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • Chloride Nucleotide-Sensitive Channel 1A; Chloride Conductance Regulatory Protein ICln; Chloride Channel, Nucleotide Sensitive 1A; Chloride Ion Current Inducer Protein; Methylosome Subunit PICln; Reticulocyte PICln; I(Cln)

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