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NativeExtract™ Recombinant Full Length Human KCIP1 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW216)

This product is recombinant Human KCIP1 protein in native nanodisc form. The synthetic compound we developed can solubilize the KCIP1 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KCIP1
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 26.8 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • KCIP1
  • Full Name
  • Potassium Voltage-Gated Channel Interacting Protein 1
  • Introduction
  • This gene encodes a member of the family of cytosolic voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the neuronal calcium sensor (NCS) family of the calcium binding EF-hand proteins. They associate with Kv4 alpha subunits to form native Kv4 channel complexes. The encoded protein may regulate rapidly inactivating (A-type) currents, and hence neuronal membrane excitability, in response to changes in the concentration of intracellular calcium. Alternative splicing results in multiple transcript variants encoding different isoforms.
  • Alternative Names
  • Potassium Voltage-Gated Channel Interacting Protein 1; A-Type Potassium Channel Modulatory Protein 1; Kv Channel Interacting Protein 1; Vesicle APC-Binding Protein; KCHIP1; VABP; Potassium Channel Interacting Protein 1; Potassium Channel-Interacting Protein 1; Kv Channel-Interacting Protein 1

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