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NativeExtract™ Recombinant Full Length Human KCD17 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW263)

This product is recombinant Human KCD17 protein in native nanodisc form. The synthetic compound we developed can solubilize the KCD17 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KCD17
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 35.7 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • KCD17
  • Full Name
  • Potassium Channel Tetramerization Domain Containing 17
  • Introduction
  • This gene encodes a protein that belongs to a conserved family of potassium channel tetramerization domain (KCTD)-containing proteins. The encoded protein functions in ciliogenesis by acting as a substrate adaptor for the cullin3-based ubiquitin-conjugating enzyme E3 ligase, and targets trichoplein, a keratin-binding protein, for degradation via polyubiquitinylation. A mutation in this gene is associated with autosomal dominant myoclonic dystonia 26.
  • Alternative Names
  • Potassium Channel Tetramerization Domain Containing 17; Potassium Channel Tetramerisation Domain Containing 17

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