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MemDX™ Recombinant Full Length Human SLC10A1/NTCP Protein (Biotinylated Nanodisc, Rho1D4 Tag) (CAT#: SYF-0926-CW163)

Recombinant full-length human SLC10A1/NTCP protein reconstituted in a biotinylated nanodisc membrane-mimetic system for immobilization, binding, detection, and assay development applications; the copolymer is biotinylated while the protein itself remains unmodified.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SLC10A1/NTCP
  • Protein Length
  • Full-length
  • Protein Class
  • Solute Carrier (SLC) Transporter
  • Molecular Weight
  • 39 kDa
  • Sequence
  • MEAHNASAPFNFTLPPNFGKRPTDLALSVILVFMLFFIMLSLGCTMEFSKIKAHLWKPKGLAIALVAQYGIMPLTAFVLGKVFRLKNIEALAILVCGCSPGGNLSNVFSLAMKGDMNLSIVMTTCSTFCALGMMPLLLYIYSRGIYDGDLKDKVPYKGIVISLVLVLIPCTIGIVLKSKRPQYMRYVIKGGMIIILLCSVAVTVLSAINVGKSIMFAMTPLLIATSSLMPFIGFLLGYVLSALFCLNGRCRRTVSMETGCQNVQLCSTILNVAFPPEVIGPLFFFPLLYMIFQLGEGLLLIAIFWCYEKFKTPKDKTKMIYTAATTEETIPGALGNGTYKGEDCSPCTA

Product Description

  • Expression Systems
  • HEK293 cells
  • Tag
  • The construct includes a C-terminal Rho1D4 tag. The copolymer is biotinylated; the protein itself is unmodified.
  • Protein Format
  • Nanodisc
  • Purity
  • The protein purity is greater than 90% as determined by SDS-PAGE.

Target

  • Target Protein
  • SLC10A1/NTCP
  • Full Name
  • solute carrier family 10 member 1
  • Introduction
  • Hepatic sodium/bile acid cotransporter (SLC10A1/NTCP) is a full-length human slc transporter. The hepatic sodium/bile acid cotransporter is a critical transporter of conjugated bile salts from the plasma into the hepatocyte, and it is also involved in the enterohepatic circulation of bile salts, which are necessary for the solubilisation and absorption of dietary fat and fat-soluble vitamins. In addition, the NTCP functions as a receptor for the hepatitis B and D virus. The surrounding nanodisc copolymer is biotinylated to support direct surface immobilization without modifying the protein itself. The preparation uses 2-step purification.
  • Alternative Names
  • NTCP, NTCP1

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