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MemDX™ Recombinant Full Length Human SLC20A2 Protein (Nanodisc, Rho1D4 Tag) (CAT#: SYF-0926-CW172)

Datasheet
Recombinant full-length human SLC20A2 protein reconstituted in a nanodisc membrane-mimetic system for biochemical, binding, and assay development applications.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SLC20A2
  • Protein Length
  • Full-length
  • Protein Class
  • Solute Carrier (SLC) Transporter
  • Molecular Weight
  • 72 kDa
  • Sequence
  • MAMDEYLWMVILGFIIAFILAFSVGANDVANSFGTAVGSGVVTLRQACILASIFETTGSVLLGAKVGETIRKGIIDVNLYNETVETLMAGEVSAMVGSAVWQLIASFLRLPISGTHCIVGSTIGFSLVAIGTKGVQWMELVKIVASWFISPLLSGFMSGLLFVLIRIFILKKEDPVPNGLRALPVFYAATIAINVFSIMYTGAPVLGLVLPMWAIALISFGVALLFAFFVWLFVCPWMRRKITGKLQKEGALSRVSDESLSKVQEAESPVFKELPGAKANDDSTIPLTGAAGETLGTSEGTSAGSHPRAAYGRALSMTHGSVKSPISNGTFGFDGHTRSDGHVYHTVHKDSGLYKDLLHKIHIDRGPEEKPAQESNYRLLRRNNSYTCYTAAICGLPVHATFRAADSSAPEDSEKLVGDTVSYSKKRLRYDSYSSYCNAVAEAEIEAEEGGVEMKLASELADPDQPREDPAEEEKEEKDAPEVHLLFHFLQVLTACFGSFAHGGNDVSNAIGPLVALWLIYKQGGVTQEAATPVWLLFYGGVGICTGLWVWGRRVIQTMGKDLTPITPSSGFTIELASAFTVVIASNIGLPVSTTHCKVGSVVAVGWIRSRKAVDWRLFRNIFVAWFVTVPVAGLFSAAVMALLMYGILPYV

Product Description

  • Expression Systems
  • HEK293 cells
  • Tag
  • The construct includes a C-terminal Rho1D4 tag.
  • Protein Format
  • Nanodisc
  • Purity
  • The protein purity is greater than 90% as determined by SDS-PAGE.

Target

  • Target Protein
  • SLC20A2
  • Full Name
  • solute carrier family 20 member 2
  • Introduction
  • Sodium-dependent phosphate transporter 2 (SLC20A2) is a full-length human slc transporter. The solute carrier family 20 member 2 is a sodium-dependent inorganic phosphate cotransporter that plays a critical role in maintaining cellular phosphate homeostasis by mediating the transport of Pi across plasma membranes. It is also essential for the regulation of mineral deposition in the brain, a process that involves preventing the pathological accumulation of calcium phosphate in the vascular extracellular matrix. Mutations in this gene have been linked to primary familial brain calcification, a neurodegenerative condition characterized by bilateral deposits in the basal ganglia and other cerebral regions. The protein is supplied in an MSP-free, copolymer-stabilized native-lipid nanodisc. The preparation uses 2-step purification.
  • Alternative Names
  • PiT-2, Glvr-2, Ram-1, PIT2, MLVAR, GLVR2

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