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MemDX™ Recombinant Full Length Human SLC25A15 Protein (Nanodisc, Rho1D4 Tag) (CAT#: SYF-0926-CW176)

Recombinant full-length human SLC25A15 protein reconstituted in a nanodisc membrane-mimetic system for biochemical, binding, and assay development applications.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SLC25A15
  • Protein Length
  • Full-length
  • Protein Class
  • Mitochondrial Carrier
  • Molecular Weight
  • 34 kDa
  • Sequence
  • MKSNPAIQAAIDLTAGAAGGTACVLTGQPFDTMKVKMQTFPDLYRGLTDCCLKTYSQVGFRGFYKGTSPALIANIAENSVLFMCYGFCQQVVRKVAGLDKQAKLSDLQNAAAGSFASAFAALVLCPTELVKCRLQTMYEMETSGKIAKSQNTVWSVIKSILRKDGPLGFYHGLSSTLLREVPGYFFFFGGYELSRSFFASGRSKDELGPVPLMLSGGVGGICLWLAVYPVDCIKSRIQVLSMSGKQAGFIRTFINVVKNEGITALYSGLKPTMIRAFPANGALFLAYEYSRKLMMNQLEAY

Product Description

  • Expression Systems
  • HEK293 cells
  • Tag
  • The construct includes a C-terminal Rho1D4 tag.
  • Protein Format
  • Nanodisc
  • Purity
  • The protein purity is greater than 90% as determined by SDS-PAGE.

Target

  • Target Protein
  • SLC25A15
  • Full Name
  • solute carrier family 25 member 15
  • Introduction
  • Mitochondrial ornithine transporter 1 (SLC25A15) is a full-length human slc transporter. SLC25A15 plays a key role in the urea cycle by exchanging cytosolic ornithine for mitochondrial citrulline, thereby transporting ornithine into the mitochondrial matrix. Pathogenic variants in this gene lead to hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome, a disorder marked by elevated ammonia levels and progressive neurological impairment. The protein is supplied in an MSP-free, copolymer-stabilized native-lipid nanodisc. The preparation uses 2-step purification.
  • Alternative Names
  • ORC1, lnc-HC, D13S327, ORNT1, HHH

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