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Recombinant Human CCR4 Full-Length Membrane Protein, MNP (CAT#: SYF-0826-CW21)

This product contains recombinant full-length human CCR4 expressed in HEK293 cells and presented in a membrane nanoparticle format with a C-terminal Flag tag.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CCR4
  • Protein Length
  • 360 aa
  • Protein Class
  • Chemokine receptor; Class A GPCR
  • Molecular Weight
  • 41.4 kDa
  • TMD
  • 7

Product Description

  • Activity
  • Validated by ELISA; antibody-binding EC50: 308.3 ng/mL.
  • Application
  • ELISA; Flow cytometry; Antibody binding and screening studies
  • Expression Systems
  • HEK293 expression system
  • Tag
  • C-Terminal Flag Tag
  • Protein Format
  • Membrane Nanoparticle (MNP)
  • Buffer
  • PBS, pH 7.4, with 5-8% trehalose as a lyoprotectant

Target

  • Target Protein
  • CCR4
  • Full Name
  • C-C motif chemokine receptor 4
  • Introduction
  • CCR4 is a chemokine receptor activated mainly by CCL17 and CCL22. It directs trafficking of T-cell subsets and is involved in allergic inflammation and T-cell malignancies.
  • Alternative Names
  • CC-CKR-4; CD194; ChemR13; CKR4; CMKBR4

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