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NativeExtract™ Biotinylated Recombiant Human P2RX1 Membrane Protein ( Full Length, Super Nanodisc) (CAT#: SYF-0826-CW33)

This product is biotinylated recombinant Human P2RX1 protein in native nanodisc form. The synthetic compound we developed can solubilize the GCGR protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • P2RX1
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 45 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • C-terminal FLAG & Avi Tag
  • Protein Format
  • Nanodisc
  • Reconstitution
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0
  • Conjugation
  • Biotinylated
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • P2RX1
  • Full Name
  • purinergic receptor P2X 1
  • Introduction
  • P2RX1 (purinergic receptor P2X 1) is an ATP-gated, non-selective cation channel belonging to the P2X receptor family. Upon ATP binding, P2RX1 mediates rapid influx of Ca²⁺ and Na⁺ and contributes to platelet activation, smooth muscle contraction, vascular regulation, and neuronal signaling. This product contains biotinylated full-length recombinant human P2RX1 incorporated into a Super Nanodisc to provide a native-like lipid environment and support preservation of its membrane-associated conformation. The incorporated Flag and Avi tags facilitate detection, immobilization, and assay development, making the product suitable for antibody discovery, ligand-binding studies, drug screening, and functional characterization of P2RX1-targeting molecules.
  • Alternative Names
  • P2X1

Case Studies

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