Introduction of GNRHR2
The putative gonadotropin-releasing hormone II receptor (GNRHR2) is a receptor protein encoded by gene GNRHR2. This receptor is a member of the G-protein coupled receptor 1 (GPCR1) family and expressed in many tissues. Putative receptor for gonadotropin releasing hormone II (GnRH II) is most probably non-functional.
|Protein Name||Putative gonadotropin-releasing hormone II receptor|
|Aliases||GnRH II receptor, GnRH-II-R, GNRR2, Type II GnRH receptor|
|Organism||Homo sapiens (Human)|
Function of GNRHR2 Membrane Protein
GNRHR2 is a receptor for gonadotropin-releasing hormone II (GnRH2). The role of GnRH2 and its receptors in mammals has been elusive, probably due to the lack of ligands and receptors in common laboratory models. In fact, GnRH2 and its receptors are not physiological regulators of gonadotropin secretion in mammals. In peripheral tissues, GnRH2 and its receptors are new regulators of the reproductive organs.
Application of GNRHR2 Membrane Protein in Literature
This article reports that GnRH2 and its receptors can coordinate the interaction between nutritional status and sexual behavior in female brains, helping to mediate female placental function, implantation and ovarian steroidogenesis.
This article reveals that GNRH2 and GNRHR2 mediate LH-independent testosterone secretion in pig testes.
This research demonstrates that NF-κB, SP1/3 and overlapping EGR1/SP1/3 binding sites are pivotal to the expression of the porcine Gnrhr2 gene in ST cells.
GNRHR2 Preparation Options
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