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MemDX™ Membrane Protein Human WFS1 (Wolframin ER transmembrane glycoprotein) Full Length (CAT#: MPC1455K) Made to Order

Datasheet
This product is a 100.2 kDa Human WFS1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • WFS1
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 100.2 kDa
  • TMD
  • 11
  • Sequence
  • MDSNTAPLGPSCPQPPPAPQPQARSRLNATASLEQERSERPRAPGPQAGP
    GPGVRDAAAPAEPQAQHTRSRERADGTGPTKGDMEIPFEEVLERAKAGDP
    KAQTEVGKHYLQLAGDTDEELNSCTAVDWLVLAAKQGRREAVKLLRRCLA
    DRRGITSENEREVRQLSSETDLERAVRKAALVMYWKLNPKKKKQVAVAEL
    LENVGQVNEHDGGAQPGPVPKSLQKQRRMLERLVSSESKNYIALDDFVEI
    TKKYAKGVIPSSLFLQDDEDDDELAGKSPEDLPLRLKVVKYPLHAIMEIK
    EYLIDMASRAGMHWLSTIIPTHHINALIFFFIVSNLTIDFFAFFIPLVIF
    YLSFISMVICTLKVFQDSKAWENFRTLTDLLLRFEPNLDVEQAEVNFGWN
    HLEPYAHFLLSVFFVIFSFPIASKDCIPCSELAVITGFFTVTSYLSLSTH
    AEPYTRRALATEVTAGLLSLLPSMPLNWPYLKVLGQTFITVPVGHLVVLN
    VSVPCLLYVYLLYLFFRMAQLRNFKGTYCYLVPYLVCFMWCELSVVILLE
    STGLGLLRASIGYFLFLFALPILVAGLALVGVLQFARWFTSLELTKIAVT
    VAVCSVPLLLRWWTKASFSVVGMVKSLTRSSMVKLILVWLTAIVLFCWFY
    VYRSEGMKVYNSTLTWQQYGALCGPRAWKETNMARTQILCSHLEGHRVTW
    TGRFKYVRVTDIDNSAESAINMLPFFIGDWMRCLYGEAYPACSPGNTSTA
    EEELCRLKLLAKHPCHIKKFDRYKFEITVGMPFSSGADGSRSREEDDVTK
    DIVLRASSEFKSVLLSLRQGSLIEFSTILEGRLGSKWPVFELKAISCLNC
    MAQLSPTRRHVKIEHDWRSTVHGAVKFAFDFFFFPFLSAA

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • WFS1
  • Full Name
  • Wolframin ER transmembrane glycoprotein
  • Introduction
  • This gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system. Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6), also known as DFNA14 or DFNA38. Alternatively spliced transcript variants have been found for this gene.
  • Alternative Names
  • WFS1; WFS; WFRS; WFSL; CTRCT41; wolframin; Wolfram syndrome 1 (wolframin); Wolframin ER transmembrane glycoprotein

Case Studies

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