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NativeExtract™ Human PROM1 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX438)

Datasheet
This product is recombinant Human PROM1 protein in native nanodisc form. The synthetic compound we developed can solubilize the PROM1 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • PROM1
  • Protein Length
  • Full length
  • Molecular Weight
  • 97.2 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • PROM1
  • Full Name
  • Prominin 1
  • Introduction
  • This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • PROM1; RP41; AC133; CD133; MCDR2; STGD4; CORD12; PROML1; MSTP061; prominin-1; antigen AC133; hProminin; hematopoietic stem cell antigen; prominin-like protein 1; Prominin 1

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