Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
Highlights| Protein Name | Neuropeptide Y receptor type 2 |
| Gene Name | NPY2R |
| Uniprot | P49146 (Human); P97295 (Mouse) |
| Synonym | NPY2-R; neuropeptide Y receptor type 2; NPY-Y2 receptor; NPY2R; Neuropeptide Y receptor Y2 |
| Background | Neuropeptide Y receptor 2 (NPY2R) is a protein that in humans is encoded by the NPY2R gene, and is a member of the Neuropeptide Y receptor family. It also belongs to the G-protein-coupled receptor superfamily. NPY receptor family comprises four functional NPY receptor subtypes (Y1R, Y2R, Y4R Y5R), it exerts a variety of physiological processes in humans via four different receptor subtypes, which are widely distributed in the central and peripheral nervous system and involved in the regulation of numerous physiological functions. |
Creative Biolabs offers comprehensive range of membrane protein products empowers your unique research needs.
| CAT# | Product Name | Expression System | Protein Length | Solubilizing Agents |
| S01YF-1023-KX142 | NativeExtract™ Human NPY2R Membrane Protein (Full length, Super Nanodisc) | HEK293 cells | Full length | Native Nanodisc |
| MPX3506K | MemDX™ Membrane Protein Human NPY2R (Neuropeptide Y receptor Y2) Expressedin vitro E.coli expression system, Full Length | E. coli cell-free | Full length | Detergent |
| MP0808X | MemDX™ Membrane Protein Human NPY2R (Neuropeptide Y receptor Y2) with N-GST tag for Antibody Discovery | Wheat germ cell-free | Full length | N/A |
| MP0807X | MemDX™ Membrane Protein Human NPY2R (Neuropeptide Y receptor Y2) without tag for Antibody Discovery | Wheat germ cell-free | Full length | Liposome |
| Please contact us for more products or customization | ||||
Fig.1 Membrane Protein Human NPY2R (MPX3506K) in Native-PAGE under reducing (R) condition. The purity of the protein is greater than 85%. The protein migrates as about 53 kDa.
Creative Biolabs can provide customized production service to support target selection rationale and preparing different antigen formats. We can produce NPY2R protein in detergents, liposomes, VLPs, nanodiscs, polymers formats.
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Ligand Binding Assays
Ligand binding assays are powerful tools for studying molecular interactions and have wide-ranging applications in research and diagnostics. Creative Biolabs offers NPY2R ligand binding assays to study the binding affinity and specificity of ligand-target interactions.
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Agonists or Antagonists Screening
Agonists bind to a target and elicit a biological response, while antagonists block the action of agonists or inhibit the target's activity. Creative Biolabs provides a NPY2R functional assays for agonists or antagonists screening.
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G Protein Activation Assays
G protein activation assays are essential for studying the mechanisms of receptor signaling, receptor heteromerization, and the dynamics of GPCR trafficking. Creative Biolabs can determine NPY2R interacts with different G protein such as Gs, Gi, Gq, G12/13, etc.
Creative Biolabs can provide different NPY2R antigen formats, including purified membrane proteins in detergent/liposome/VLPs/nanodiscs/polymers, extracellular regions, over-expressed whole cells, and DNA or mRNA encoding NPY2R.
We have established different platforms and processes to advance the antibody discovery.
With our innovative approaches and comprehensive services, Creative Biolabs is dedicated to advancing NPY2R gene therapy. We provide tailored solutions to meet your specific requirements. Please inquire us for more services.
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Overexpression of NPY2R
Creative Biolabs offers Overexpression Cell Line Construction Service, utilizing AAV viral vectors or plasmid transfection methods to enable the overexpression of NPY2R in specific tissues or cells, thereby enhancing signal activity.
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Gene Knockout or Knockdown
Creative Biolabs offers Gene Knockout or Knockdown Service, utilizing gene editing technology to precisely knock out or inhibit the expression of NPY2R. This method is crucial for studying the effects of reduced NPY2R function.
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Modulation of NPY2R Signaling Pathways
Creative Biolabs provides the Modulation of NPY2R Signaling Pathways service, enabling the regulation of the MAPK pathway via gene editing or overexpression of specific signaling molecules to either enhance or inhibit NPY2R-mediated actions.
Creative Biolabs offers comprehensive and innovative services to drive the development of NPY2R cell therapy. Our commitment to excellence ensures the highest quality and reliability. Please inquire us for more services.
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Genetic Modification of Immune Cells
Creative Biolabs offers Immune Cell Gene Modification Services. T cells or other immune cells can be genetically engineered to express NPY2R or its ligands to modulate immune responses. This approach could potentially enhance the therapeutic effects of immunotherapy by targeting specific signaling pathways involved in pain or inflammation.
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NPY2R-Targeted Drug Delivery Systems
Creative Biolabs offers Targeted Drug Delivery System Service, which can be used to specifically target cells expressing NPY2R. These systems can deliver NPY2R agonists or antagonists directly to the target cells, thereby enhancing therapeutic efficacy while minimizing off-target effects.
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Combination with Other Immunotherapies
Creative Biolabs provides development and preclinical research services for combining NPY2R cell immunotherapy with other immunotherapies. This service integrates NPY2R cell immunotherapy with other therapeutic approaches. Such combination therapies can offer more comprehensive treatment strategies for complex diseases.
As a forward-looking research institute as well as a leading customer service provider in the field of membrane protein, Creative Biolabs has won good reputation among our worldwide customers for successfully accomplishing numerous challenging projects including generation of many functional membrane proteins. Please feel free to contact us for more information.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
