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NativeExtract™ Recombinant Full Length Human ACHA6 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW258)

This product is recombinant Human ACHA6 protein in native nanodisc form. The synthetic compound we developed can solubilize the ACHA6 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ACHA6
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 56.9 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • ACHA6
  • Full Name
  • Cholinergic Receptor Nicotinic Alpha 6 Subunit
  • Introduction
  • This gene encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exogenous nicotine. Alternatively spliced transcript variants have been observed for this gene. Single nucleotide polymorphisms in this gene have been associated with both nicotine and alcohol dependence.
  • Alternative Names
  • Cholinergic Receptor Nicotinic Alpha 6 Subunit; Acetylcholine Receptor, Nicotinic, Alpha 6 (Neuronal); Cholinergic Receptor, Nicotinic, Alpha Polypeptide 6; Cholinergic Receptor, Nicotinic, Alpha 6 (Neuronal); Cholinergic Receptor, Nicotinic Alpha 6; Neuronal Acetylcholine Receptor Subunit Alpha-6; CHNRA6

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