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NativeExtract™ Recombinant Full Length Human TRPM7 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW184)

This product is recombinant Human TRPM7 protein in native nanodisc form. The synthetic compound we developed can solubilize the TRPM7 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TRPM7
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 212.7 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • TRPM7
  • Full Name
  • Transient Receptor Potential Cation Channel Subfamily M Member 7
  • Introduction
  • This gene belongs to the melastatin subfamily of transient receptor potential family of ion channels. The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. The encoded protein is involved in cytoskeletal organization, cell adhesion, cell migration and organogenesis. Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam. The gene may also be associated with defects of cardiac function.
  • Alternative Names
  • Transient Receptor Potential Cation Channel Subfamily M Member 7; Long Transient Receptor Potential Channel 7; Channel-Kinase 1; EC 2.7.11.1; LTrpC-7; LTRPC7; CHAK1

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