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NativeExtract™ Recombinant Full Length Human CA2D4 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW212)

This product is recombinant Human CA2D4 protein in native nanodisc form. The synthetic compound we developed can solubilize the CA2D4 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CA2D4
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 127.9 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • CA2D4
  • Full Name
  • Calcium Voltage-Gated Channel Auxiliary Subunit Alpha2Delta 4
  • Introduction
  • This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
  • Alternative Names
  • Calcium Voltage-Gated Channel Auxiliary Subunit Alpha2delta 4; Calcium Channel, Voltage-Dependent, Alpha 2/Delta Subunit 4; Voltage-Gated Calcium Channel Subunit Alpha-2/Delta-4; Voltage-Dependent Calcium Channel Subunit Alpha-2/Delta-4; Voltage-Gated Calcium Channel Alpha(2)Delta-4 Subunit; RCD4

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