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NativeExtract™ Recombinant Full Length Human CAC1G Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW209)

This product is recombinant Human CAC1G protein in native nanodisc form. The synthetic compound we developed can solubilize the CAC1G protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CAC1G
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 262.5 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • CAC1G
  • Full Name
  • Calcium Voltage-Gated Channel Subunit Alpha1 G
  • Introduction
  • Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death. This gene encodes a T-type, low-voltage activated calcium channel. The T-type channels generate currents that are both transient, owing to fast inactivation, and tiny, owing to small conductance. T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing. Many alternatively spliced transcript variants encoding different isoforms have been described for this gene.
  • Alternative Names
  • Calcium Voltage-Gated Channel Subunit Alpha1 G; Calcium Channel, Voltage-Dependent, T Type, Alpha 1G Subunit; Voltage-Gated Calcium Channel Subunit Alpha Cav3.1; Cav3.1c; NBR13; Voltage-Dependent T-Type Calcium Channel Alpha 1G Subunit; Voltage-Dependent T-Type Calcium Channel Subunit Alpha-1G

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