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NativeExtract™ Recombinant Full Length Human CAC1S Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW150)

This product is recombinant Human CAC1S protein in native nanodisc form. The synthetic compound we developed can solubilize the CAC1S protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CAC1S
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 212.4 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • CAC1S
  • Full Name
  • Calcium Voltage-Gated Channel Subunit Alpha1 S
  • Introduction
  • CACNA1S (Calcium Voltage-Gated Channel Subunit Alpha1 S) is a Protein Coding gene. Diseases associated with CACNA1S include Hypokalemic Periodic Paralysis, Type 1 and Malignant Hyperthermia 5. Among its related pathways are Cardiac conduction and NFAT and Cardiac Hypertrophy. Gene Ontology (GO) annotations related to this gene include ion channel activity and high voltage-gated calcium channel activity. An important paralog of this gene is CACNA1C.
  • Alternative Names
  • Calcium Voltage-Gated Channel Subunit Alpha1 S; Calcium Channel, Voltage-Dependent, L Type, Alpha 1S Subunit; Voltage-Gated Calcium Channel Subunit Alpha Cav1.1; CACNL1A3; Calcium Channel, L Type, Alpha 1 Polypeptide, Isoform 3 (Skeletal Muscle, Hypokalemic Periodic Paralysis); Calcium Channel, L Type, Alpha-1 Polypeptide, Isoform 3, Skeletal Muscle; Dihydropyridine-Sensitive L-Type Calcium Channel Alpha-1 Subunit; Voltage-Dependent L-Type Calcium Channel Subunit Alpha-1S; Dihydropyridine Receptor Alpha 1 Subunit; CCHL1A3

Case Studies

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