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NativeExtract™ Recombinant Full Length Human P2RX4 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW85)

This product is recombinant Human P2RX4 protein in native nanodisc form. The synthetic compound we developed can solubilize the P2RX4 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • P2RX4
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 43.4 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • P2RX4
  • Full Name
  • Purinergic Receptor P2X 4
  • Introduction
  • The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest sensitivity for these antagonists. Multiple alternatively spliced transcript variants, some protein-coding and some not protein-coding, have been found for this gene.
  • Alternative Names
  • Purinergic Receptor P2X 4; ATP Receptor; P2X4; Purinergic Receptor P2X, Ligand-Gated Ion Channel, 4; Purinergic Receptor P2X, Ligand Gated Ion Channel, 4; ATP-Gated Cation Channel Protein; Purinergic Receptor P2X4

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