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MemDX™ Recombinant Full Length Human CD4 Protein (Biotinylated Nanodisc, Rho1D4 Tag) (CAT#: SYF-0926-CW82)

Recombinant full-length human CD4 protein reconstituted in a biotinylated nanodisc membrane-mimetic system for immobilization, binding, detection, and assay development applications; the copolymer is biotinylated while the protein itself remains unmodified.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CD4
  • Protein Length
  • Full-length
  • Protein Class
  • Immune Cell-Surface Receptor
  • Molecular Weight
  • 51 kDa (homodimer)
  • Sequence
  • MNRGVPFRHLLLVLQLALLPAATQGKKVVLGKKGDTVELTCTASQKKSIQFHWKNSNQIKILGNQGSFLTKGPSKLNDRADSRRSLWDQGNFPLIIKNLKIEDSDTYICEVEDQKEEVQLLVFGLTANSDTHLLQGQSLTLTLESPPGSSPSVQCRSPRGKNIQGGKTLSVSQLELQDSGTWTCTVLQNQKKVEFKIDIVVLAFQKASSIVYKKEGEQVEFSFPLAFTVEKLTGSGELWWQAERASSSKSWITFDLKNKEVSVKRVTQDPKLQMGKKLPLHLTLPQALPQYAGSGNLTLALEAKTGKLHQEVNLVVMRATQLQKNLTCEVWGPTSPKLMLSLKLENKEAKVSKREKAVWVLNPEAGMWQCLLSDSGQVLLESNIKVLPTWSTPVQPMALIVLGGVAGLLLFIGLGIFFCVRCRHRRRQAERMSQIKRLLSEKKTCQCPHRFQKTCSPI

Product Description

  • Expression Systems
  • HEK293 cells
  • Tag
  • The construct includes a C-terminal Rho1D4 tag. The copolymer is biotinylated; the protein itself is unmodified.
  • Protein Format
  • Nanodisc
  • Purity
  • The protein purity is greater than 90% as determined by SDS-PAGE.

Target

  • Target Protein
  • CD4
  • Full Name
  • CD4 molecule
  • Introduction
  • T-cell surface glycoprotein CD4 (CD4) is a full-length human receptor. The T-cell surface glycoprotein CD4 is a glycoprotein involved in the immune response and cell-mediated immunity. T lymphocytes that carry the CD4 surface antigen are called T helper cells and are the subtype of T lymphocytes that are primarily infected by HIV. It is therefore a target for HIV infection and immunotherapy. The surrounding nanodisc copolymer is biotinylated to support direct surface immobilization without modifying the protein itself. The preparation uses 2-step purification.
  • Alternative Names
  • T4, Leu-3

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