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NativeExtract™ Recombinant Full Length Human CXA1 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW61)

This product is recombinant Human ZACN protein in native nanodisc form. The synthetic compound we developed can solubilize the ZACN protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CXA1
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 43 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • CXA1
  • Full Name
  • Gap Junction Protein Alpha 1
  • Introduction
  • This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations.
  • Alternative Names
  • Gap Junction Protein Alpha 1; Gap Junction Protein, Alpha 1, 43kDa; Gap Junction 43 KDa Heart Protein; Connexin-43; CX43; GJAL; Gap Junction Protein, Alpha 1, 43kDa (Connexin 43); Oculodentodigital Dysplasia (Syndactyly Type III); Gap Junction Protein, Alpha-Like; Gap Junction Alpha-1 Protein

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