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MemDX™ Recombinant Full Length Human SLC20A2 Protein (Biotinylated Nanodisc, Rho1D4 Tag) (CAT#: SYF-0926-CW173)

Datasheet
Recombinant full-length human SLC20A2 protein reconstituted in a biotinylated nanodisc membrane-mimetic system for immobilization, binding, detection, and assay development applications; the copolymer is biotinylated while the protein itself remains unmodified.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SLC20A2
  • Protein Length
  • Full-length
  • Protein Class
  • Solute Carrier (SLC) Transporter
  • Molecular Weight
  • 72 kDa
  • Sequence
  • MAMDEYLWMVILGFIIAFILAFSVGANDVANSFGTAVGSGVVTLRQACILASIFETTGSVLLGAKVGETIRKGIIDVNLYNETVETLMAGEVSAMVGSAVWQLIASFLRLPISGTHCIVGSTIGFSLVAIGTKGVQWMELVKIVASWFISPLLSGFMSGLLFVLIRIFILKKEDPVPNGLRALPVFYAATIAINVFSIMYTGAPVLGLVLPMWAIALISFGVALLFAFFVWLFVCPWMRRKITGKLQKEGALSRVSDESLSKVQEAESPVFKELPGAKANDDSTIPLTGAAGETLGTSEGTSAGSHPRAAYGRALSMTHGSVKSPISNGTFGFDGHTRSDGHVYHTVHKDSGLYKDLLHKIHIDRGPEEKPAQESNYRLLRRNNSYTCYTAAICGLPVHATFRAADSSAPEDSEKLVGDTVSYSKKRLRYDSYSSYCNAVAEAEIEAEEGGVEMKLASELADPDQPREDPAEEEKEEKDAPEVHLLFHFLQVLTACFGSFAHGGNDVSNAIGPLVALWLIYKQGGVTQEAATPVWLLFYGGVGICTGLWVWGRRVIQTMGKDLTPITPSSGFTIELASAFTVVIASNIGLPVSTTHCKVGSVVAVGWIRSRKAVDWRLFRNIFVAWFVTVPVAGLFSAAVMALLMYGILPYV

Product Description

  • Expression Systems
  • HEK293 cells
  • Tag
  • The construct includes a C-terminal Rho1D4 tag. The copolymer is biotinylated; the protein itself is unmodified.
  • Protein Format
  • Nanodisc
  • Purity
  • The protein purity is greater than 90% as determined by SDS-PAGE.

Target

  • Target Protein
  • SLC20A2
  • Full Name
  • solute carrier family 20 member 2
  • Introduction
  • Sodium-dependent phosphate transporter 2 (SLC20A2) is a full-length human slc transporter. The solute carrier family 20 member 2 is a sodium-dependent inorganic phosphate cotransporter that plays a critical role in maintaining cellular phosphate homeostasis by mediating the transport of Pi across plasma membranes. It is also essential for the regulation of mineral deposition in the brain, a process that involves preventing the pathological accumulation of calcium phosphate in the vascular extracellular matrix. Mutations in this gene have been linked to primary familial brain calcification, a neurodegenerative condition characterized by bilateral deposits in the basal ganglia and other cerebral regions. The surrounding nanodisc copolymer is biotinylated to support direct surface immobilization without modifying the protein itself. The preparation uses 2-step purification.
  • Alternative Names
  • PiT-2, Glvr-2, Ram-1, PIT2, MLVAR, GLVR2

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