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NativeExtract™ Recombinant Full Length Human TRPM2 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW189)

This product is recombinant Human TRPM2 protein in native nanodisc form. The synthetic compound we developed can solubilize the TRPM2 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TRPM2
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 171.2 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • TRPM2
  • Full Name
  • Transient Receptor Potential Cation Channel Subfamily M Member 2
  • Introduction
  • The protein encoded by this gene forms a tetrameric cation channel that is permeable to calcium, sodium, and potassium and is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. Additional transcript variants of this gene have been described, but their full-length nature is not known.
  • Alternative Names
  • Transient Receptor Potential Cation Channel Subfamily M Member 2; Estrogen-Responsive Element-Associated Gene 1 Protein; Long Transient Receptor Potential Channel 2; Transient Receptor Potential Melastatin 2; Transient Receptor Potential Channel 7; LTrpC-2; LTRPC2

Case Studies

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