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NativeExtract™ Recombinant Full Length Human TRPM5 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW186)

This product is recombinant Human TRPM5 protein in native nanodisc form. The synthetic compound we developed can solubilize the TRPM5 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TRPM5
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 131.5 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • TRPM5
  • Full Name
  • Transient Receptor Potential Cation Channel Subfamily M Member 5
  • Introduction
  • This gene encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Ca(2+) ions. It is activated by lower concentrations of intracellular Ca(2+), and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5, and has been shown to be imprinted, with exclusive expression from the paternal allele.
  • Alternative Names
  • Transient Receptor Potential Cation Channel Subfamily M Member 5; Long Transient Receptor Potential Channel 5; MLSN1- And TRP-Related Gene 1 Protein; LTrpC-5; LTRPC5; MTr1; Transient Receptor Potential Cation Channel, Subfamily M, Member 5; MLSN1 And TRP-Related

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