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NativeExtract™ Recombinant Full Length Human KCNE3 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW234)

Datasheet
This product is recombinant Human KCNE3 protein in native nanodisc form. The synthetic compound we developed can solubilize the KCNE3 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KCNE3
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 11.7 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • KCNE3
  • Full Name
  • Potassium Voltage-Gated Channel Subfamily E Regulatory Subunit 3
  • Introduction
  • Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the kidney. A missense mutation in this gene is associated with hypokalemic periodic paralysis.
  • Alternative Names
  • Potassium Voltage-Gated Channel Subfamily E Regulatory Subunit 3; Potassium Channel, Voltage Gated Subfamily E Regulatory Beta Subunit 3; Potassium Voltage-Gated Channel, Isk-Related Family, Member 3; Minimum Potassium Ion Channel-Related Peptide 2; Potassium Channel Subunit Beta MiRP2; MinK-Related Peptide 2; Cardiac Voltage-Gated Potassium Channel Accessory Subunit

Case Studies

Customer reviews and Q&As    

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