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Recombinant Human FZD4 Full-Length Membrane Protein, MNP (CAT#: SYF-0826-CW11)

This product contains recombinant full-length human FZD4 expressed in HEK293 cells and presented in a membrane nanoparticle format with a C-terminal Flag tag.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • FZD4
  • Protein Length
  • 537 aa
  • Protein Class
  • Frizzled family G protein-coupled receptor
  • Molecular Weight
  • 60.3 kDa
  • TMD
  • 7

Product Description

  • Activity
  • Validated by ELISA; antibody-binding EC50: 13.75 ng/mL.
  • Application
  • ELISA; Antibody binding and screening studies
  • Expression Systems
  • HEK293 expression system
  • Tag
  • C-Terminal Flag Tag
  • Protein Format
  • Membrane Nanoparticle (MNP)
  • Buffer
  • PBS with 5-8% trehalose as a lyoprotectant

Target

  • Target Protein
  • FZD4
  • Full Name
  • frizzled class receptor 4
  • Introduction
  • FZD4 is a seven-pass receptor that participates in Wnt and Norrin signaling. It has an important role in retinal vascular development and maintenance of vascular barriers.
  • Alternative Names
  • CD344; EVR1; FEVR; Fz-4; Fz4; FZD4S; FzE4; GPCR; hFz4

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