Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsFor over two decades, Creative Biolabs has stood at the forefront of antibody innovation. As a trusted partner to the global scientific community, we combine deep immunological expertise with state-of-the-art technology to deliver high-affinity, highly specific polyclonal antibodies tailored to your precise research needs. Our comprehensive Polyclonal Antibody Discovery Services are engineered to provide robust reagents for a multitude of applications, from fundamental research to preclinical development.
Innovation is the cornerstone of our service. We continuously integrate the latest technological advancements to deliver polyclonal antibodies that meet the demands of modern research.
The success of any antibody project begins with the antigen. We offer comprehensive support, from gene synthesis and recombinant protein expression (E. coli, insect, mammalian) to peptide synthesis and modification (e.g., phosphorylation, acetylation). Our algorithm analyzes factors like hydrophilicity, surface accessibility, and sequence homology to design peptide antigens with the highest probability of generating specific and functional antibodies.
Our immunization protocols are optimized for maximum efficacy and animal welfare.
Figure 1. Structural and functional features of isotype G immunoglobulins (IgG).1
A high titer is only half the battle; purity and specificity are paramount. We employ a rigorous, multi-step purification strategy to ensure your antibody is ready for its intended application.
We have streamlined our production process into a clear, five-phase workflow, ensuring efficiency and transparency.
Phase 1: Project Consultation and Antigen Design
Phase 2: Immunization
Phase 3: Titer Monitoring (Ongoing)
Phase 4: Antibody Purification
Phase 5: Final QC and Delivery
The choice of host species can significantly impact antibody diversity and specificity, particularly concerning the phylogenetic distance to the antigen's source protein. We offer an extensive selection to meet any project requirement.
| Host Species | Key Advantages & Recommended Applications |
| Rabbit | The most popular choice. Produces high-affinity IgG antibodies with excellent avidity. Ideal for WB, IHC, ELISA, and IP. |
| Mouse / Rat | Cost-effective and fast. Suitable for generating antibodies against antigens from species other than rodents. Useful for pilot studies. |
| Goat / Sheep | Larger blood volume allows for large-scale production of antiserum. Excellent for generating secondary antibodies and for targets where high quantities are needed. |
| Chicken (IgY) | Phylogenetically distant from mammals, making them ideal for generating antibodies against highly conserved mammalian proteins. IgY antibodies do not bind to Fc receptors or Protein A/G, reducing background in certain assays. |
| Alpaca / Llama | Produce unique heavy-chain-only antibodies (VHH), the source of single domain antibody. Useful for specialized applications and recognizing cryptic epitopes. |
| Guinea Pig | Often used when rabbit or mouse hosts fail to produce a sufficient immune response. |
Our polyclonal antibodies are validated for a wide range of immunoassays. We can also perform custom validation upon request.
Choosing a CRO for your antibody discovery project is a critical decision. With Creative Biolabs, you gain a partner dedicated to your success, offering a unique combination of experience, technology, and client-focused support.
| Our Advantage | Description |
| Decades of Expertise | With over 20 years of hands-on experience, our Ph.D.-level scientists have successfully executed thousands of polyclonal antibody projects, troubleshooting every conceivable challenge. |
| High Success Rate | We proudly maintain a >95% success rate, even for the most difficult antigens, including small molecules, phosphopeptides, and complex transmembrane proteins. |
| Advanced Immunization Platforms | We utilize proprietary adjuvant formulations and cutting-edge immunization strategies, such as our Adjuvant System and Fast-Track 45-Day Protocol, to elicit potent, high-titer immune responses. |
| Diverse Host Species | Our accredited facilities house a wide range of host species, allowing us to select the optimal host to maximize immunoreactivity against your specific target. |
| Comprehensive Antigen Design | We offer complimentary, in-silico antigen design using our proprietary Antigen-Epitope Prediction algorithm to ensure the resulting antibodies recognize the native protein in your desired application. |
| Flexible & Transparent Process | From initial consultation to final delivery, we offer customizable project plans and maintain open communication, providing regular updates and expert support. |
Ready to develop a powerful new tool for your research? Contact our team of experts to discuss your project. Provide us with your target details, and we will deliver a customized, no-obligation proposal within 24 hours.
Q: What is the typical timeline for a standard rabbit polyclonal antibody project?
A: Our standard protocol is approximately 13-14 weeks, from antigen synthesis to delivery of the purified antibody. We also offer expedited services.
Q: How much antigen do I need to provide?
A: For a standard project in two rabbits, we typically require 3-5 mg of recombinant protein or 5-10 mg of a KLH-conjugated peptide. Our project managers will provide precise quantities based on your specific project plan.
Q: Can you generate antibodies against a difficult target?
A: Absolutely. This is our specialty. With our advanced adjuvant technology, diverse host options, and expert antigen design strategies, we have a proven track record of success with targets that have failed elsewhere.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
