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NativeExtract™ Recombinant Full Length Human ACHA3 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW255)

This product is recombinant Human ACHA3 protein in native nanodisc form. The synthetic compound we developed can solubilize the ACHA3 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ACHA3
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 57.5 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • ACHA3
  • Full Name
  • Cholinergic Receptor Nicotinic Alpha 3 Subunit
  • Introduction
  • This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.
  • Alternative Names
  • Cholinergic Receptor Nicotinic Alpha 3 Subunit; Cholinergic Receptor, Nicotinic, Alpha Polypeptide 3; Cholinergic Receptor, Nicotinic, Alpha 3 (Neuronal); Cholinergic Receptor, Nicotinic Alpha 3; NACHRA3; Neuronal Nicotinic Acetylcholine Receptor, Alpha3 Subunit

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