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NativeExtract™ Recombinant Full Length Human KCNE1 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW107)

Datasheet
This product is recombinant Human KCNE1 protein in native nanodisc form. The synthetic compound we developed can solubilize the KCNE1 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KCNE1
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 14.7 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • KCNE1
  • Full Name
  • Potassium Voltage-Gated Channel Subfamily E Regulatory Subunit 1
  • Introduction
  • The product of this gene belongs to the potassium channel KCNE family. Potassium ion channels are essential to many cellular functions and show a high degree of diversity, varying in their electrophysiologic and pharmacologic properties. This gene encodes a transmembrane protein known to associate with the product of the KVLQT1 gene to form the delayed rectifier potassium channel. Mutation in this gene are associated with both Jervell and Lange-Nielsen and Romano-Ward forms of long-QT syndrome. Alternatively spliced transcript variants encoding the same protein have been identified.
  • Alternative Names
  • Potassium Voltage-Gated Channel Subfamily E Regulatory Subunit 1; Potassium Channel, Voltage Gated Subfamily E Regulatory Beta Subunit 1; IKs Producing Slow Voltage-Gated Potassium Channel Subunit Beta Mink; Potassium Voltage-Gated Channel, Isk-Related Family, Member 1; Delayed Rectifier Potassium Channel Subunit IsK; Minimal Potassium Channel; Potassium Voltage-Gated Channel, Isk-Related Subfamily, Member 1; Potassium Voltage-Gated Channel Subfamily E Member 1; Cardiac Delayed Rectifier Potassium Channel Protein

Case Studies

Customer reviews and Q&As    

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