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NativeExtract™ Recombinant Full Length Human BEST4 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW165)

This product is recombinant Human BEST4 protein in native nanodisc form. The synthetic compound we developed can solubilize the BEST4 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • BEST4
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 53.5 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • BEST4
  • Full Name
  • Bestrophin 4
  • Introduction
  • This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 4 gene is predominantly expressed in the colon.
  • Alternative Names
  • Bestrophin 4; Vitelliform Macular Dystrophy 2-Like Protein 2; Vitelliform Macular Dystrophy 2-Like 2; VMD2L2; Bestrophin-4

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