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NativeExtract™ Recombinant Full Length Human ASIC1 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW129)

This product is recombinant Human ASIC1 protein in native nanodisc form. The synthetic compound we developed can solubilize the ASIC1 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ASIC1
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 59.9 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • ASIC1
  • Full Name
  • Acid Sensing Ion Channel Subunit 1
  • Introduction
  • This gene encodes a member of the acid-sensing ion channel (ASIC) family of proteins, which are part of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Members of the ASIC family are sensitive to amiloride and function in neurotransmission. The encoded proteins function in learning, pain transduction, touch sensation, and development of memory and fear. Alternatively spliced transcript variants have been described.
  • Alternative Names
  • Acid Sensing Ion Channel Subunit 1; Amiloride-Sensitive Cation Channel 2, Neuronal; Acid Sensing (Proton Gated) Ion Channel 1; Brain Sodium Channel 2; ACCN2; BNaC2
  • Gene ID
  • 41

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