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NativeExtract™ Recombinant Full Length Human KCNH6 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW254)

This product is recombinant Human KCNH6 protein in native nanodisc form. The synthetic compound we developed can solubilize the KCNH6 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KCNH6
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 109.9 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • KCNH6
  • Full Name
  • Potassium Voltage-Gated Channel Subfamily H Member 6
  • Introduction
  • Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. Alternative splicing results in multiple transcript variants that encode different isoforms.
  • Alternative Names
  • Potassium Voltage-Gated Channel Subfamily H Member 6; Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 6; Voltage-Gated Potassium Channel Subunit Kv11.2; Ether-A-Go-Go-Related Protein 2; HERG-2; HERG2; ERG-2

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