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MemDX™ Recombinant Full Length Human CD20 Protein (Biotinylated Nanodisc, Rho1D4 Tag) (CAT#: SYF-0926-CW78)

Recombinant full-length human CD20 protein reconstituted in a biotinylated nanodisc membrane-mimetic system for immobilization, binding, detection, and assay development applications; the copolymer is biotinylated while the protein itself remains unmodified.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CD20
  • Protein Length
  • Full-length
  • Protein Class
  • MS4A Family Membrane Protein
  • Molecular Weight
  • 38 kDa (homotetramer)
  • Sequence
  • MTTPRNSVNGTFPAEPMKGPIAMQSGPKPLFRRMSSLVGPTQSFFMRESKTLGAVQIMNGLFHIALGGLLMIPAGIYAPICVTVWYPLWGGIMYIISGSLLAATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMDILNIKISHFLKMESLNFIRAHTPYINIYNCEPANPSEKNSPSTQYCYSIQSLFLGILSVMLIFAFFQELVIAGIVENEWKRTCSRPKSNIVLLSAEEKKEQTIEIKEEVVGLTETSSQPKNEEDIEIIPIQEEEEEETETNFPEPPQDQESSPIENDSSP

Product Description

  • Expression Systems
  • HEK293 cells
  • Tag
  • The construct includes a C-terminal Rho1D4 tag. The copolymer is biotinylated; the protein itself is unmodified.
  • Protein Format
  • Nanodisc
  • Purity
  • The protein purity is greater than 90% as determined by SDS-PAGE.

Target

  • Target Protein
  • CD20
  • Full Name
  • membrane spanning 4-domains A1
  • Introduction
  • B-lymphocyte surface antigen CD20 (CD20) is a full-length human receptor. B-lymphocyte antigen CD20 is a surface protein on B cells that is essential for regulating B cell activation. The general function of CD20 is to maintain an optimal B cell immune response, particularly against T cell-independent antigens. CD20 is also associated with certain types of cancer, as it is a type of tumor marker. The surrounding nanodisc copolymer is biotinylated to support direct surface immobilization without modifying the protein itself. The preparation uses 2-step purification.
  • Alternative Names
  • B1, Bp35, FMC7, CD20

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