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NativeExtract™ Recombinant Full Length Human CLCA1 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW118)

This product is recombinant Human CLCA1 protein in native nanodisc form. The synthetic compound we developed can solubilize the CLCA1 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CLCA1
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 100.2 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • CLCA1
  • Full Name
  • Chloride Channel Accessory 1
  • Introduction
  • This gene encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The encoded protein may be involved in mediating calcium-activated chloride conductance in the intestine.
  • Alternative Names
  • Chloride Channel Accessory 1; Chloride Channel, Calcium Activated, Family Member 1; Calcium-Activated Chloride Channel Family Member 1; Calcium-Activated Chloride Channel Protein 1; Chloride Channel Regulator 1; HCaCC-1; CaCC-1; HCLCA1; CACC1

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