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NativeExtract™ Recombinant Full Length Human GRIK2 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW124)

Datasheet
This product is recombinant Human GRIK2 protein in native nanodisc form. The synthetic compound we developed can solubilize the GRIK2 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GRIK2
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 102.6 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • GRIK2
  • Full Name
  • Glutamate Ionotropic Receptor Kainate Type Subunit 2
  • Introduction
  • Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive cognitive disability.
  • Alternative Names
  • Glutamate Ionotropic Receptor Kainate Type Subunit 2; Excitatory Amino Acid Receptor 4; Glutamate Receptor 6; GluR-6; GLUR6; GluK2; EAA4; Glutamate Receptor, Ionotropic, Kainate 2; Glutamate Receptor Ionotropic, Kainate 2; Glutamate Receptor Form A

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