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NativeExtract™ Recombinant Full Length Human TRPC4 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW194)

This product is recombinant Human TRPC4 protein in native nanodisc form. The synthetic compound we developed can solubilize the TRPC4 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TRPC4
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 112.1 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • TRPC4
  • Full Name
  • Transient Receptor Potential Cation Channel Subfamily C Member 4
  • Introduction
  • This gene encodes a member of the canonical subfamily of transient receptor potential cation channels. The encoded protein forms a non-selective calcium-permeable cation channel that is activated by Gq-coupled receptors and tyrosine kinases, and plays a role in multiple processes including endothelial permeability, vasodilation, neurotransmitter release and cell proliferation. Single nucleotide polymorphisms in this gene may be associated with generalized epilepsy with photosensitivity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
  • Alternative Names
  • Transient Receptor Potential Cation Channel Subfamily C Member 4; Trp-Related Protein 4; HTRP-4; HTRP4; Transient Receptor Potential Cation Channel, Subfamily C, Member 4; Short Transient Receptor Potential Channel 4; TrpC4; TRP4

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