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MemDX™ Recombinant Full Length Human DRD1 Protein (Biotinylated Nanodisc, Rho1D4 Tag & FLAG Tag) (CAT#: SYF-0926-CW114)

Recombinant full-length human DRD1 protein reconstituted in a biotinylated nanodisc membrane-mimetic system for immobilization, binding, detection, and assay development applications; the copolymer is biotinylated while the protein itself remains unmodified.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • DRD1
  • Protein Length
  • Full-length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 52 kDa
  • Sequence
  • MKTIIALSYIFCLVFADYKDDDDKENLYFQGRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPTGSSGTETSQVAPA

Product Description

  • Expression Systems
  • Trichoplusia ni insect cells
  • Tag
  • The construct includes an N-terminal HA signal peptide, FLAG tag, and TEV cleavage site, together with a C-terminal Rho1D4 tag. The copolymer is biotinylated; the protein itself is unmodified.
  • Protein Format
  • Nanodisc
  • Purity
  • The protein purity is greater than 90% as determined by SDS-PAGE.

Target

  • Target Protein
  • DRD1
  • Full Name
  • dopamine receptor D1
  • Introduction
  • D(1) dopamine receptor (DRD1) is a full-length human gpcr. The Dopamine Receptor D1 (DRD1) mediates essential functions in motor control, reward, and cognition by stimulating cAMP production in the brain. Its therapeutic relevance lies in managing Parkinson's disease and cognitive impairment, where selective targeting helps restore neurological balance with fewer side effects than non-selective treatments. The surrounding nanodisc copolymer is biotinylated to support direct surface immobilization without modifying the protein itself. The preparation uses 2-step purification.
  • Alternative Names
  • D1R

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