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NativeExtract™ Recombinant Full Length Human GBRA1 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW270)

This product is recombinant Human GBRA1 protein in native nanodisc form. The synthetic compound we developed can solubilize the GBRA1 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GBRA1
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 51.8 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • GBRA1
  • Full Name
  • Gamma-Aminobutyric Acid Type A Receptor Alpha1 Subunit
  • Introduction
  • This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene.
  • Alternative Names
  • Gamma-Aminobutyric Acid Type A Receptor Alpha1 Subunit; Gamma-Aminobutyric Acid (GABA) A Receptor, Alpha 1; GABA(A) Receptor Subunit Alpha-1; GABA(A) Receptor, Alpha 1; Gamma-Aminobutyric Acid Receptor Subunit Alpha-1; EIEE19; ECA4; EJM5; EJM

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