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NativeExtract™ Recombinant Full Length Human KCIP4 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW248)

This product is recombinant Human KCIP4 protein in native nanodisc form. The synthetic compound we developed can solubilize the KCIP4 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KCIP4
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 28.7 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • KCIP4
  • Full Name
  • Potassium Voltage-Gated Channel Interacting Protein 4
  • Introduction
  • This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein member also interacts with presenilin. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
  • Alternative Names
  • Potassium Voltage-Gated Channel Interacting Protein 4; A-Type Potassium Channel Modulatory Protein 4; Kv Channel Interacting Protein 4; Calsenilin-Like Protein; KCHIP4; CALP; Potassium Channel-Interacting Protein 4; Kv Channel-Interacting Protein 4

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